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The pathological state of glial cells regulates the bloodbrain barrier (De Bock et al., 2017) and therefore these cells can be thought of as guardians that protect neurons against oxidative stress (Liu et al., 2018) via the Saposin C/GPR37L1/GPR37 pathway
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Umumararungu T, Gahamanyi N, Mukiza J, et al
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Imaging glutathione depletion in the rat brain using ascorbate-derived hyperpolarized MR and PET probes
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